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Research Compounds

MOTS-c and SLU-PP-332: AMPK and ERR Signaling Research

By Vault Peptides 2 min read

These compounds are studied in cultured cells for their interaction with cellular energy-sensing pathways. MOTS-c and SLU-PP-332 represent two distinct approaches to studying exercise-responsive signaling in laboratory settings.

MOTS-c: The Mitochondrial-Derived Peptide

MOTS-c is a 16-amino acid peptide encoded by the mitochondrial genome (12S rRNA gene). Research has examined its effects on AMPK activation, glucose metabolism, fatty acid oxidation, and cellular stress resistance. As a mitochondrially-derived peptide, MOTS-c provides researchers with a unique tool for studying mitochondrial-nuclear communication in metabolic regulation.

SLU-PP-332: Exercise Pathway Activator

SLU-PP-332 is a small molecule studied for its effects on ERR (estrogen-related receptor) signaling pathways, which play key roles in mitochondrial biogenesis and oxidative metabolism. Research has examined its effects on gene-expression programs and AMPK phosphorylation readouts in cultured cells.

Research Applications

Both compounds are used in studies examining AMPK phosphorylation, ERR receptor binding, mitochondrial biogenesis markers, and oxygen consumption rate in cultured cells.

Availability

MOTS-c in 10mg and 40mg. SLU-PP-332 in 5mg concentrations. Analytical documentation is published where available.

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AMPKmitochondriaMOTS-cSLU-PP-332
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For laboratory and research use only (RUO). Not for human or veterinary use, ingestion, or therapeutic application. These statements have not been evaluated by the FDA. No product is intended to diagnose, treat, cure, or prevent any disease.

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