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Neuropeptide Chemistry

Semax and Selank: ACTH(4-10) and Tuftsin Peptide Analogs

By Vault Peptides 2 min read

Semax and Selank are distinct synthetic heptapeptides discussed in experimental neuroscience literature. Semax is an ACTH-fragment analog with the sequence MEHFPGP; Selank is a tuftsin analog with the sequence TKPRPGP. Their shared peptide length does not make their identities or study results interchangeable.

Semax: a defined experimental model

Dolotov and colleagues investigated Semax binding in rat basal forebrain membrane preparations and measured brain-derived neurotrophic factor responses in rats. Those measurements describe the particular experimental systems in the publication; they do not establish a clinical outcome or characterize a Vault batch.

Primary source: Dolotov and colleagues’ Semax binding and BDNF study, Journal of Neurochemistry (2006).

Selank: gene-expression measurements

Volkova and colleagues examined expression of neurotransmission-related genes in rat frontal cortex in a 2016 Selank study. Its gene-expression measurements should be interpreted within that model and study design, rather than generalized to people or assumed to describe another peptide.

Primary source: Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission, Frontiers in Pharmacology (2016).

Separate current catalog listings

  • Semax 10mg: lyophilized powder, listed sequence MEHFPGP.
  • Selank 10mg: lyophilized powder, listed sequence TKPRPGP.

Review each product’s own specifications and match its batch identifier against the relevant COA record. Published compound research and a supplied batch’s analytical report are separate evidence sources.

Disclaimer: All products referenced in this article are intended for laboratory and research use only. They are not intended for human consumption. By purchasing from Vault Peptides, you acknowledge these products are for research purposes only and agree to comply with all applicable laws and regulations. Vault Peptides does not make any claims regarding efficacy or safety for non-research applications.

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Research compounds referenced

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Browse the Vault catalog of research peptides. Independent-lab certificates of analysis are published on the listings where they are available.

For laboratory and research use only (RUO). Not for human or veterinary use, ingestion, or therapeutic application. These statements have not been evaluated by the FDA. No product is intended to diagnose, treat, cure, or prevent any disease.

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